Product ID:NEOSPORIN PRODUCTS
MSDS Date:10/31/1994
FSC:6505
NIIN:01-143-4644
MSDS Number: BXNZR

BURROUGHS WELLCOME CO

INTERSECTION US 13 AND S R 1590
GREENVILLE, NC 27835-1887
US

Emergency Phone: 919-758-3436

Info Phone: 919-758-3436

Cage: 09979

BURROUGHS WELLCOME CO

RESEARCH TRIANGLE PARK, NC 27709 US

Telephone: 919-248-3000

Cage: 09979

POLYMYXIN B SULFATE

CAS: 1405-20-5

RTECS: TR1150000

NEOMYCIN SULFATE

CAS: 1405-10-3

RTECS: QP4375000

BACITRACIN

CAS: 1405-87-4

RTECS: CP0175000

LIDOCAINE (BASE)

CAS: 137-58-6

RTECS: AN7525000

LD50 LC50 Mixture:ORAL LD50 (MOUSE): 8 MG/KG (SEE SUPP)
Routes of Entry: Inhalation:YES Skin:NO Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:POLYMYXIN B
SULFATE-NEUROTOXICITY/NEPHROTOXICITY/NEUROMUSCULAR
BLOCKADE/SYSTEMIC POLYMYXIN POISONING/KIDNEY DAMAGE/SENSITIZATION.
NEOMYCIN SULFATE-HYPERSENSITIVITY REACTIONS/SEVERE RENAL
TOXICITY/NEUR OTOXICITY/OTOTOXICITY/NEUROMUSCULAR
BLOCKADE/RESPIRATORY PARALYSIS. BACITRACIN ZINC-IRRITATION/ALLERGIC
REACTIONS (SUPP)
Explanation of Carcinogenicity:NONE
Effects of Overexposure:POLYMYXIN B SULFATE-FEVER. NEOMYCIN
SULFATE-RASH, HEARING LOSS, DIMINISHED BALANCE. BACITRACIN
ZINC-IRRITATION. LIDOCAINE-IRRITATION.

First Aid:EYES: RINSE IMMEDIATELY W/PLENTY OF WATER. INHALATION: REMOVE
TO FRESH AIR. KEEP WARM & QUIET. GIVE CPR IF NEEDED. INGESTION:
WASH OUT MOUTH. GIVE PLENTY OF WATER/BLAND FLUIDS. UNLESS VOMITING
IS COPI OUS, LAVAGE SHOULD BE CARRIED OUT. SKIN: WASH OFF W/PLENTY
OF WATER. OBTAIN MEDICAL ATTENTION IN ALL CASES.

Extinguishing Media:USE AGENT APPROPRIATE TO NATURE OF FIRE & OTHER
MATERIALS INVOLVED.
Fire Fighting Procedures:WEAR SELF CONTAINED BREATHING APPARATUS.

Spill Release Procedures:WIPE/MOP UP MATERIAL. WASH ALL CONTAMINATED
SURFACES W/SOAP & WATER. PLACE WASTE IN APPROPRIATE CONTAINER FOR
DISPOSAL.

Handling and Storage Precautions:STORE IN ORIGINAL CONTAINER TIGHTLY
CLOSED.
Other Precautions:AVOID SKIN & EYE CONTACT.

Respiratory Protection:NONE NECESSARY.
Ventilation:NONE NECESSARY.
Protective Gloves:LATEX
Work Hygienic Practices:REMOVE/LAUNDER CONTAMINATED CLOTHING BEFORE
REUSE.
Supplemental Safety and Health
ORAL LD50 INFORMATION IS FOR POLYMYXIN B SULFATE. HEALTH HAZARDS
CONT'D: NEPHROTOXICITY. LIDOCAINE-EYE/SKIN/RESPIRATORY TRACT
IRRITATION, TOPICAL ANESTHESIA. INGESTION IS TOXIC.

Appearance and Odor:REFER TO PRODUCT LABEL/INSERT FOR SPECIFIC PRODUCT
DESCRIPTION

Stability Indicator/Materials to Avoid:YES
Hazardous Decomposition Products:TOXIC/IRRITANT FUMES.

Waste Disposal Methods:DISPOSE OF IAW/FEDERAL, STATE & LOCAL
REGULATIONS.

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.